Joe Mixon ran for three touchdowns, Derek Barnett returned a fumble 28 yards for a score and the Houston Texans beat the Dallas Cowboys 34-10.

Dak Prescott threw a touchdown pass hours after agreeing to a four-year, $240 million contract with Dallas and the Cowboys’ defense roughed up Deshaun Watson in his return, throttling the Cleveland Browns 33-17 in their opener.

Dak Prescott threw two of his four touchdown passes to CeeDee Lamb, DaRon Bland recorded his NFL-leading third interception return for a score and the Dallas Cowboys beat the Los Angeles Rams 43-20.

Brock Purdy threw three of his four touchdown passes to George Kittle and the San Francisco 49ers extended their dominance over the Dallas Cowboys with a 42-10 victory.

KaVontae Turpin became the first player in nine seasons to have kickoff and punt return touchdowns in the same game, and the Dallas Cowboys beat the Los Angeles Chargers 32-18.

KaVontae Turpin is getting his first chance in the NFL with the Dallas Cowboys nearly four years after the receiver and kick returner was accused of assaulting his girlfriend, ending his career at TCU.