As part of our Ask 2 series, the newsroom will answer your questions about all things Houston. Question: Does Xlear nasal spray really work to fight against COVID-19? “Studies show that regular nasal cleansing may help reduce viral infections, including from the SARS-CoV-2 virus (COVID-19),” Ferrer said. On Dec. 8, 2020, Xlear submitted a Pre-Emergency Use Authorization request to the U.S. Food and Drug Administration. People should be using Xlear as part of a layered defense to prevent getting COVID-19.