Fast forward to now, those neighborhoods are hot spots for COVID-19. KPRC 2 Investigations analyzed this data to locate the areas with the highest COVID-19 infection rates. In Manchester, a Latino community in southeast Houston, the COVID-19 infected rate is 44 per 10,000 residents. Other Houston hot spots need some context. The Texas Medical Center also has a high infection rate of 124 per 10,000 people.